Data/hora: 18/05/2024 17:25:05

Provedor de dados: 	Genetics and Molecular Biology	
País: 	Brazil	
Título: 	Polycythemia and Hb Coimbra [beta 99 (G1) Asp -&gt; Glu] in Brazil	
Autores: 	Fattori,André; Kimura,Elza Miyuki; Albuquerque,Dulcinéia Martins de; Ogo,Satie Hatsushika; Stoppa,Graziela Renata; Martins,Juliana Touquinha; Lima,Carmen Silvia Passos; Saad,Sara Terezinha Ollala; Costa,Fernando Ferreira; Sonati,Maria de Fátima.	
Data: 	2006-01-01	
Ano: 	2006	
Palavras-chave: 	Polycythemia; Erythrocytosis; Hb Coimbra; Beta-globin gene.	
Resumo: 	We report the clinical and laboratory findings concerning three unrelated Brazilian patients investigated for polycythemia, whose definitive diagnosis could only be established after the presence of Hb Coimbra (b99 Asp ® Glu) was demonstrated. This illustrates the importance of properly investigating hereditary hemoglobinopathies in cases of erythrocytosis because in some populations variants with high oxygen affinity may be more frequent than expected but go undetected when conventional electrophoresis is used as the sole detection procedure.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572006000200002	
Editor: 	Sociedade Brasileira de Genética	
Relação: 	10.1590/S1415-47572006000200002	
Formato: 	text/html	
Fonte: 	Genetics and Molecular Biology  v.29 n.2 2006	
Fonte: 	info:eu-repo/semantics/openAccess